8-CHLORO-11-(1-FORMYL-4-PIPERIDYLIDENE)-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDINE
N-Formyl Desloratadine
CAS: 117810-61-4
Molecular Formula: C20H19ClN2O
8-CHLORO-11-(1-FORMYL-4-PIPERIDYLIDENE)-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDINE - Names and Identifiers
8-CHLORO-11-(1-FORMYL-4-PIPERIDYLIDENE)-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDINE - Physico-chemical Properties
| Molecular Formula | C20H19ClN2O |
| Molar Mass | 338.83 |
| Density | 1.323±0.06 g/cm3(Predicted) |
| Melting Point | 147-149 °C |
| Boling Point | 543.2±50.0 °C(Predicted) |
| Solubility | Chloroform (Slightly), DMSO (Very Slightly), Methanol (Slightly, Sonicated) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 4.17±0.20(Predicted) |
| Storage Condition | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
| Stability | Light Sensitive |
8-CHLORO-11-(1-FORMYL-4-PIPERIDYLIDENE)-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDINE - Risk and Safety
| HS Code | 2933399090 |
8-CHLORO-11-(1-FORMYL-4-PIPERIDYLIDENE)-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDINE - Introduction
N-Formyldesloratadine (N-Formyl Desloratadine) is an impurity of Desloratadine. Dloratadine is a second-generation antihistamine that is commonly used to relieve allergic symptoms, such as sneezing, runny nose, and itching. N-formyldesloratadine is a product of the decomposition or oxidation of desloratadine.
The chemical properties of N-formyl desloratadine are: the molecular formula is C19H17ClN2O2, and the relative molecular mass is 344.80g/mol. The appearance is a white crystalline solid with a melting point of around 150°C. It is the acylation product of desloratadine, obtained by introducing a formyl group into the desloratadine molecule.
The use of N-formyl desloratadine is mainly used as a pharmaceutical intermediate in the synthesis of desloratadine. This impurity is produced due to the instability of desloratadine under certain conditions. It can reduce its production by optimizing the synthesis process and controlling the reaction conditions to improve the quality of desloratadine products.
With regard to safety information, the toxicological and physiological properties of N-formyl desloratadine are not fully understood. However, it is generally believed that under normal use and storage conditions, it is less harmful to the human body and the environment. However, appropriate safety measures such as wearing gloves, eye protection and use of ventilation equipment are still required when handling the substance. In addition, in the event of any contact with or ingestion of the substance, immediate medical attention should be sought and appropriate first aid measures provided.
The chemical properties of N-formyl desloratadine are: the molecular formula is C19H17ClN2O2, and the relative molecular mass is 344.80g/mol. The appearance is a white crystalline solid with a melting point of around 150°C. It is the acylation product of desloratadine, obtained by introducing a formyl group into the desloratadine molecule.
The use of N-formyl desloratadine is mainly used as a pharmaceutical intermediate in the synthesis of desloratadine. This impurity is produced due to the instability of desloratadine under certain conditions. It can reduce its production by optimizing the synthesis process and controlling the reaction conditions to improve the quality of desloratadine products.
With regard to safety information, the toxicological and physiological properties of N-formyl desloratadine are not fully understood. However, it is generally believed that under normal use and storage conditions, it is less harmful to the human body and the environment. However, appropriate safety measures such as wearing gloves, eye protection and use of ventilation equipment are still required when handling the substance. In addition, in the event of any contact with or ingestion of the substance, immediate medical attention should be sought and appropriate first aid measures provided.
Last Update：2024-04-09 21:04:16
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Spot supply
Product Name: Loratadine Impurity 12 Visit Supplier Webpage Request for quotationCAS: 117810-61-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: N-Formyl Desloratadine Visit Supplier Webpage Request for quotation
CAS: 117810-61-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 117810-61-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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